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PROVAZA is a vascular protector and a venotonic agent that stimulates venous bloodstream. It also has a venous analgesic effect (or vasodilator), i.e. it dilates the veins and allows better blood circulation. PROVAZA can be used for the symptomatic treatment of heavy legs, pain, restlessness and other disorders that may be related to venous or lymphatic circulation and even for hemorrhoidal crisis.
Oedema usually occurs first by weight gain followed by heavy and swollen legs. Women are the most affected. The lower limb oedema makes walking difficult. However, simple gestures and treatments as well as taking some natural supplements can help solve this problem.
Approved by Health Canada. NPN: 80042363
Recommended Dose: 1 tablet 2 times daily
- Diosmin (Fruit bioflavonoids - Citrus aurantium): 450 mg
- Hesperidin (Fruit bioflavonoids - Citrus aurantium): 50 mg
- Ginkgo biloba (24/6 extract) :15 mg
- Vitamin C (Ascorbic Acid): 50 mg
- Struckmann JR, Nicolaides AN. Flavonoids. A review of the pharmacology and therapeutic efficacy of Daflon 500 mg in patients with chronic venous insufficiency and related disorders. Angiology. 1994;45(6):419-28. PubMed PMID: 8203767.
- Nicolaides AN. From symptoms to leg edema: efficacy of Daflon 500 mg. Angiology. 2003;54 Suppl 1:S33-44. PubMed PMID: 12934755.
- Ramelet AA. Clinical benefits of Daflon 500 mg in the most severe stages of chronic venous insufficiency. Angiology. 2001;52 Suppl 1:S49-56. PubMed PMID: 11510597.
- Pan HP. [Progress in studies of pharmacological activities and clinical applications of preparations of dried leaf of Ginkgo biloba]. Zhongguo Zhong Yao Za Zhi. 2005;30(2):93-6. PubMed PMID: 15714808.
- Priollet P, Boisseau MR. [Drugs for veno-lymphatic insufficiency]. Rev Prat. 2000;50(11):1195-8. PubMed PMID: 11008499.
- McKenna DJ, Jones K, Hughes K. Efficacy, safety, and use of ginkgo biloba in clinical and preclinical applications. Altern Ther Health Med. 2001;7(5):70-86, 8-90. PubMed PMID: 11565403.
- Chen X, Touyz RM, Park JB, Schiffrin EL. Antioxidant effects of vitamins C and E are associated with altered activation of vascular NADPH oxidase and superoxide dismutase in stroke-prone SHR. Hypertension. 2001;38(3 Pt 2):606-11. PubMed PMID: 11566940.
- Santilli F, D'Ardes D, Davi G. Oxidative stress in chronic vascular disease: From prediction to prevention. Vascul Pharmacol. 2015. doi: 10.1016/j.vph.2015.09.003. PubMed PMID: 26363473.