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PROZEN may play a role in relieving pain associated with PMS, menstruation and migraines. PROZEN can also significantly reduce morning sickness related to pregnancy. It is also used in cases of nervous and/or muscle fatigue, irritability, tiredness, minors sleep disorders, palpitations, muscle cramps and tingling.
Magnesium and vitamin B6 play a role in balancing the nervous system by reducing fatigue and helping to maintain normal muscle contraction. The magnesium assimilation is enhanced by vitamin B6 improving efficiency.
Approved by Health Canada. NPN: 80037175
Recommended Dose: 1 tablet 3 times daily
- Magnesium (HvP Chelate): 150 mg
- Vitamin B6 (Pyridoxine HCL):10 mg
- Seelig, M. S. Consequences of magnesium deficiency on the enhancement of stress reactions; preventive and therapeutic implications (a review). J Am Coll Nutr 13, 429-446 (1994).
- De Souza, M. C., Walker, A. F., Robinson, P. A. & Bolland, K. A synergistic effect of a daily supplement for 1 month of 200 mg magnesium plus 50 mg vitamin B6 for the relief of anxiety-related premenstrual symptoms: a randomized, double-blind, crossover study. J Womens Health Gend Based Med 9, 131-139, doi:10.1089/152460900318623 (2000).
- De Baaij, J. H., Hoenderop, J. G. & Bindels, R. J. Magnesium in man: implications for health and disease. Physiol Rev 95, 1-46, doi:10.1152/physrev.00012.2014 (2015).
- Guerrera, M. P., Volpe, S. L. & Mao, J. J. Therapeutic uses of magnesium. Am Fam Physician 80, 157-162 (2009).
- Wibowo, N. et al. Vitamin B(6) supplementation in pregnant women with nausea and vomiting. Int J Gynaecol Obstet 116, 206-210, doi:10.1016/j.ijgo.2011.09.030 (2012).
- Matok, I. et al. Studying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugs. J Clin Pharmacol 54, 1429-1433, doi:10.1002/jcph.369 (2014).
- Vutyavanich, T., Wongtra-ngan, S. & Ruangsri, R. Pyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial. Am J Obstet Gynecol 173, 881-884 (1995).
- Chittumma, P., Kaewkiattikun, K. & Wiriyasiriwach, B. Comparison of the effectiveness of ginger and vitamin B6 for treatment of nausea and vomiting in early pregnancy: a randomized double-blind controlled trial. J Med Assoc Thai 90, 15-20 (2007).
- Jewell, D. & Young, G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev, CD000145, doi:10.1002/14651858.CD000145 (2003).